The sections below will provide you with more specific information and guidelines related to sulfasalazine and its correct use. Sulfasalazine (SSZ), sold under the trade name Azulfidine among others, is a medication used to treat rheumatoid arthritis, ulcerative colitis, and Crohn’s disease. The safety and effectiveness of sulfasalazine have not been established for children younger than 2 years of age. Do not take sulfasalazine without first talking to your doctor if you have ever had an allergic reaction to sulfasalazine, a sulfa-based antibiotic, or aspirin; an obstruction (blockage) in your intestines or urinary tract; porphyria; liver disease; kidney disease; asthma; or glucose-6-phosphate dehydrogenase deficiency. All rights reserved. headache Pee that is dark 13. Manufacturer: PHARMACIA / UPJHN. The more common side effects that can occur with sulfasalazine include: drowsiness If you experience any of the following serious side effects, stop taking sulfasalazine and seek emergency medical attention or notify your doctor immediately: an allergic reaction (difficulty breathing, closing of your throat, swelling of your lips, tongue, or face, or hives) What special precautions should I follow? This is normal and nothing to worry about. Stomach upset, nausea, vomiting, loss of appetite, headache, dizziness, or unusual tiredness may occur. Stomach Cramps 11. If you experience any of the following serious side effects, stop taking sulfasalazine and seek emergency medical attention or notify your doctor immediately: an allergic reaction (difficulty breathing, closing of your throat, swelling of your lips, tongue, or face, or hives) worsening colitis (fever, abdominal pain, cramping, or bloody diarrhea) ©1999-2017 Anakena Internet Services S.L. If experienced, these tend to have a Severe expression 1. Mayo Clinic does not endorse companies or products. This medication works by reducing irritation and swelling in the large intestines. Azulfidine Consumer Information. It may also cause other side effects. Aching of muscles black, tarry stools blistering, peeling, or loosening of the skin bloating blood in the urine or stools bloody diarrhea bluish fingernails, lips, or skin chest pain constipation cough difficulty with swallowing dizziness fainting spells fast heartbeat … You may need to take folate supplements or eat folate-rich foods. Imprint: 104 Back, leg, or stomach pains 9. bleeding gums 10. bluish colour of the fingernails, lips, skin, palms, or nail beds 11. chills 12. Strength(s): 500 MG Serious skin reactions can occur with this medicine. Do not stop taking sulfasalazine, even if you begin to feel better, without first talking to your doctor. Manufacturer: GREENSTONE LTD, Name: SULFASALAZINE Sulfasalazine Side Effects Stomach upset, nausea, vomiting, loss of appetite, headache, dizziness, or unusual tiredness may occur. pale skin Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Side effects can occur earlier. In addition, delayed-release tablets of sulfasalazine are used to treat rheumatoid arthritis and juvenile rheumatoid arthritis. Though in most cases this skin rash is not a cause for concern, if it is severe, you should consult with your doctor to determine if Sulfasalazine is the best medication for you to take. Symptoms may include: skin rash, fever, swollen … received an overall rating of 6 out of 10 stars from 10 reviews. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. Summary: We compare the side effects and drug effectiveness of Sulfasalazine and Enbrel. Sulfasalazine may cause your skin to be more sensitive to sunlight than it is normally. Store it at room temperature and away from excess heat and moisture (not in the bathroom). - Rash had the appearance of an exfoliative dermatitis bordering on a SJ syndrome (diffuse MP rash with an erythematous/scaly background); there were no oral lesions. What are the possible side effects of sulfasalazine? When you begin taking this medicine: Trouble breathing 14. Your skin or urine may turn an orange or yellow color while you or your child are using this medicine. abdominal pain Commonly these include loss of appetite, nausea, headache, and rash. This medicine may increase your risk of developing infections. Hi Fellow RA sufferers, after 7 months of taking Sulfasalazine I've had to stop due to a nasty rash & terrible itching on my arms lower legs & back. Imprint: MP 91 If you plan to have children, talk with your doctor before using this medicine. They are specially formulated to release the medication after they have passed through your stomach. Side effects — The major side effects of sulfasalazine can be classified according to how frequently the side effect occurs: commonly, uncommonly, and rarely. sore throat rashes. Strength(s): 500 MG Some patients may require a product with a higher SPF number, especially if they have a fair complexion. Abnormal Urine Color 2. Take sulfasalazine exactly as directed by your doctor. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter. Currently, this drug is approved by the US Food and Drug Administration (FDA) for the treatment of ulcerative colitis and rheumatoid arthritis. A severe adverse reaction to sulfasalazine has been identified as a type of hypersensitivity syndrome. Sulfasalazine helps to reduce joint pain, swelling, and stiffness. A prescription is required for this medicine. This site complies with the HONcode standard for trustworthy health information: verify here. Also tell your doctor if you have ever had an infection that would not go away or an infection that kept coming back. Appetite loss 6. You may not be able to take sulfasalazine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. Most patients start to feel the positive effects of at 4-8 weeks, with maximum benefit at 3-6 months. Throwing Up Sulfasalazine can have a number of side-effects, many of which are minor. Sulfasalazine has also been used for some skin conditions. After an attack is treated, sulfasalazine is also used to increase the amount of time between attacks. Rash was 4+ acute and covered 100% of the body. CAS nº: 599-79-1 Call your doctor if you find an undissolved delayed-release (Azulfidine EN-tabs®) tablet in your stool. Sulfasalazine (SSZ), sold under the trade name Azulfidine among others, is a medication used to treat rheumatoid arthritis, ulcerative colitis, and Crohn's disease. The case of an overdose, call your doctor treatment of both juvenile and adult RA as regular and (! 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